Sulpiride Tablets is a substituted benzamide derivative and a selective dopamine D2 antagonist indicated to treat acute and chronic schizophrenia.6,7,8,10 It has a short duration of action since it is administered twice daily and a window extensive therapy as patients have survived. single doses up to 16 g.10 Patients should be counseled about increased motor agitation, extrapyramidal reactions, and neuroleptic malignant syndrome.
Sulpiride is a selective antagonist of dopamine D2 and D3 receptors.6,7,8 In silico studies show that sulpiride can interact with amino acid residues Asp-119 and Phe-417 of these receptors.8 It is estimated that D2 receptors should be 65-80% occupied for optimal treatment and minimal adverse effects.
SULPIRIDE 25mg Tablet 2x10s works by inhibiting the acti
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